ic50 values against chk1 (ICE Bioscience)
90
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ICE Bioscience
ic50 values against chk1
Ic50 Values Against Chk1, supplied by ICE Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ic50+values+against+chk1/ic50+values+against+chk1/pm38547734-334-0-7
Average 90 stars, based on 1 article reviews
Ic50 Values Against Chk1, supplied by ICE Bioscience, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ic50+values+against+chk1/ic50+values+against+chk1/pm38547734-334-0-7
Average 90 stars, based on 1 article reviews
ic50 values against chk1 - by Bioz Stars,
2026-10
90/100 stars
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Related Articles
other:Article Title: Discovery of pyrido[3,2-d]pyrimidin-6(5H)-one derivatives as checkpoint kinase 1 (CHK1) inhibitors with potent antitumor efficacy. Article Snippet: Checkpoint kinase 1 (CHK1) plays a crucial role in the DNA damage response pathway, making it an attractive target for cancer therapy.. Herein, we present the synthesis, optimization, and evaluation of selective CHK1 inhibitors with a pyrido[3,2-d]pyrimidin-6(5H)-one scaffold.. Among them, compound 11 showed single-digit nanomolar potency against CHK1 (IC50: 0.55 nM) with good kinase selectivity. |